Table 1 Antimicrobial activity of selected RD dyes against four Gram-positive and four Gram-negative bacteria

From: A diversity-oriented rhodamine library for wide-spectrum bactericidal agents with low inducible resistance against resistant pathogens

 

Gram-positive organism

Gram-negative organism

MIC (μg mL−1)

ATCC43300

ATCC25923

ATCC51299

ATCC29212

ATCC19606

ATCC13883

ATCC25922

ATCC27853

RD1

1

0.5

16

16

/

/

/

/

RD12

/

/

/

/

8

128

64

128

RD15

1

0.5

32

16

/

/

/

/

RD22

1

0.5

2

2

4

16

16

16

RD31

0.5

0.5

16

16

/

/

/

/

RD44

/

/

/

/

4

32

8

16

RD45

1

1

8

4

4

64

16

16

RD46

1

1

2

2

/

/

/

/

RD53

1

1

2

2

4

16

8

16

vancomycin

2

2

/

4

/

/

/

/

linezolid

1

/

2

2

/

/

/

/

polymyxin E

/

/

/

/

1

/

/

1

tigecycline

2

/

1

/

2

/

/

/

daptomycin

2

/

4

/

/

/

/

/

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