Fig. 7
From: A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing
EMC assembly is critical for nuclear retention of gametogenic gene transcripts in mitotic cells. a Representative images of the EMC target ssm4 mRNA (red) detected by Single molecule RNA Fluorescence In-Situ Hybridization (smFISH). DNA was stained with DAPI (blue). Images are shown as the maximum-intensity projections of Z-stacks. Dotted lines indicate the outline of cells. Scale bar (white) represents 5 μm. b Quantification of nuclear and cytoplasmic localization of ssm4 mRNA. The upper panel shows the mean ± SEM from more than 140 cells and the lower panel indicates the distribution of the percentages of ssm4 mRNA spots/cell
