Fig. 1 | Nature Communications

Fig. 1

From: Neuropathological correlates and genetic architecture of microglial activation in elderly human brain

Fig. 1

Flowchart of analyses performed in this study. ROS Religious Orders Study, MAP Memory and Aging Project, PAM proportion of activated microglia, AD Alzheimer’s disease, FUMAGWAS functional mapping and annotation of genome-wide association studies, IMAS Indiana Memory and Aging Study, GTEx Genotype and Tissue Expression Study, BRAINEAC Brain eQTL Almanac, CADD combined annotation-dependent depletion, MSigDB the Molecular Signature Database. Beta amyloid figure adapted from Darvesh, Hopkins & Geula (2003) https://www.nature.com/articles/nrn1035#rightslink. Neurofibrillary tangles figure adapted from Alzheimer (1911) Ueber eigenartige Krankheitsfaelle des spaeteren Alters (10.1177/0957154×9100200506)

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