Fig. 3 | Nature Communications

Fig. 3

From: Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs

Fig. 3

Effect of transcription on cisplatin-induced damage formation and repair. Genes are grouped based on their gene expression quantiles (x-axis) in the cisplatin-treated group. Log normalized read counts for DNA damage and repair (y-axis) are separated by strands and averaged between replicates. Spearman correlation coefficients are included in each panel. TCR increases with gene expression and removes damage in the TS strand; GR also increases with gene expression, but at a lower rate

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