Fig. 2

Gut bacteria harboring tyrosine decarboxylases are responsible for levodopa decarboxylation. a Aligned genomes of E. faecium, E. faecalis, and L. brevis. The conserved tdc-operon is depicted with tdc gene in orange. Overnight cultures of b E. faecalis v583, c E. faecium W54, and d L. brevis W63 incubated anaerobically at 37 °C with 100 µM of levodopa (LD). e Overnight cultures of EFSWT and EFSΔTDC incubated anaerobically at 37 °C with 100 μM levodopa (black line) compared to control (gray line) where no levodopa was added. Curves represent one example of three biological replicates