Fig. 6
From: A five-residue motif for the design of domain swapping in proteins
Domain swapping in Sso7dv and UBQ. a Structure of Sso7d (PDB ID: 1BNZ) is shown. Different secondary structural elements, the N-termini and C-termini, and loop1, loop2, and loop3 of Sso7d are indicated. b Size exclusion profiles of Sso7dv, L1Sso7dv, and L1Sso7dv*, at pH 7.5, are shown. L1Sso7dv* is a variant of L1Sso7dv, in which the QVVAG sequence was mutated to QVNAG. Elution volumes corresponding to the monomeric and dimeric species are indicated. c Structure of human ubiquitin (UBQ) (PDB ID: 1UBQ) is shown. Different secondary structural elements, the N-termini and C-termini, and loop1 and loop4 of UBQ are indicated. d Size exclusion profiles of UBQ, L4UBQ, L4UBQ* and L4UBQ** at pH 8.3, are shown. L4UBQ* and L4UBQ** are variants of L4UBQ, in which the QVVAG sequence was mutated to QVNAG and QNNAG, respectively. The elution volumes of the monomer (M), dimer (D) and the void fraction (V) are indicated. Source data are provided as a Source Data file
