Fig. 2
From: Functional role of PGAM5 multimeric assemblies and their polymerization into filaments
Architecture of the PGAM5 dodecameric ring in solution and in a new crystal structure. a 2D class average of the predominant view of the ring assembly observed in cryo-EM micrographs of ∆48 PGAM5 reveals a dodecameric topology highly similar in architecture to b. b 2D projection image of the crystallographic ring observed in the crystal lattice of ∆54 PGAM5 (PDB: 5MUF) limited to 4.5 Å resolution. c Architecture and subunit arrangement of the dodecameric assembly observed in the crystal structure of the ∆90 PGAM5 H105A phosphatase domain crystallized in the presence of a peptide containing the multimerization motif (MM)
