Table 1 Asymmetric [3+2] coupling of 3-substituted indoles with quinone monoimine^a

^aReaction conditions: 3-substituted indole (0.10 mmol), quinone monoimine (0.15 mmol), and (S)-1-Ni (0.04 mol% catalyst based on indole) in CH₃CN (1 mL), 0 °C, 14 h
^bIsolated yield
^cDetermined by HPLC
^dReaction time: 48 h
^ePIME = phthalimidoethyl (size: 6.5 × 15.2 Å², Supplementary Figure 13)
^fThe R enantiomer was produced using (R)-1-Ni as the catalyst
^gCatalyzed by 0.24 mol% of benzoic acid
^hCatalyzed by 0.03 mol% of the discrete cage 1-Ni* and 0.24 mol% of (S)-Me₄L

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