Fig. 7 | Nature Communications

Fig. 7

From: ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail

Fig. 7

A fuzzy charge–charge interaction enhances PP1α C-tail binding to ASPP2. a Fully annotated 2D [1H,15N] HSQC of PP1301-330. b 2D [1H,15N] HSQC of PP1301-330 (black) in presence of a 2 (violet) or 4 (green) molar excess of ASPP2. c Comparative analysis of 15N[1H] NOE of free PP1α C-tail (black bars) and PP1α C-tail: ASPP2 (grey bars); missing peaks are due to overlap, making quantitative intensity analysis impossible. Error bars represent standard deviations. d Comparative analysis of 15N transverse relaxation (R2) data of free PP1α C-tail (black bars) and PP1α C-tail: ASPP2 (grey bars). Error bars represent standard deviations

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