Table 1 Up- and downregulated genes in 14-day-starved cells

From: Extreme slow growth as alternative strategy to survive deep starvation in bacteria

Gene

Function

Fold upregulation 14 days/exp

Fold upregulation 14 days/stat

abnA

Arabinan degradation

3.1

2.6

acoA, acoB, acoC

Acetoin utilization

8.5, 4.8, 2.0

12.7, 3.4, 2.3

araB, araD, araL, araN, araP, araQ

Arabinose utilization

2.3, 2.6, 2.4, 2.1, 3.6, 3.6

2.2, 2.0, 2.2, 2.3, 2.1, 2.5

araE

Uptake of arabinose, galactose, and xylose

2.1

2.0

cwlT

Conjugative transfer of ICEBs1

2.5

2.2

czcD

Cation efflux, resistance against Zn, Cu, Co, Ni

2.6

2.7

exuT

Hexuronate uptake

2.1

3.1

ganB

Galactan utilization

2.9

3.4

hutH

Histidine utilization

2.4

2.2

manA

Mannose utilization

2.7

2.2

mmgB

Mother cell metabolism

32.5

4.4

nicK

Conjugation of ICE BS1

4.7

3.9

rbsC, rbsD

Ribose uptake

3.5, 3.1

2.1, 2.3

rhiF

Uptake of rhamnose oligosaccharides

2.5

4.3

sigV

Resistance to lytic enzymes

2.8

3.6

uxaC, uxuA

Hexuronate utilization

2.5, 2.0

3.0, 2.1

ydfQ

Unknown

2.2

3.5

ydfR

Unknown

19.7

2.7

ydzR

Unknown

4.3

3.6

yezD

Unknown

3.4

4.1

yisJ

Unknown

17.2

3.0

  

Fold downregulation 14 days/exp

Fold downregulation 14 days/stat

bioI

Biosynthesis of biotin

−2.3

−2.1

comC

Genetic competence

−2.4

−3.0

comGC, comGD, comGE, comGF, comGG

Genetic competence

−3.1, −3.3, −2.8, −3.1, −3.4

−3.5, −3.5, −2.9, −3.0, −2.4

coxA

Resistance of the spore

−2.7

−2.1

epsD, epsI, epsJ, epsL

Biofilm formation

−4.6, −8.1, −4.6, 8.4

−2.8, −4.5, −3.1, −5.0

nadA, nadC

NAD biosynthesis

−2.1, −2.4

−2.0, −2.3

rtpA

Regulation of tryptophan biosynthesis

−4.2

−2.6

tasA

Biofilm formation

−5.1

−2.7

thiS

Biosynthesis of thiamine

−3.5

−3.5

thiU

Thiamine uptake

−2.2

−2.2

yckD

Unknown

−3.9

−2.4

ywcJ

Unknown

−2.0

−2.3

ywpE

Unknown

−23.6

−8.3

  1. The transcriptome profile of 14-day-starved cells was compared to those of exponential phase and stationary phase cells. Genes that showed at least a twofold up- or downregulation in both situations, with p-values lower than 0.05, are listed. Genes in an operon have been grouped together