Table 1 Clinical and laboratory characteristics of case-patients

From: The indirect health effects of malaria estimated from health advantages of the sickle cell trait

Characteristic

HbAA

HbAS

P value

All admissions (n, %)

16,502 (90.21)

1791 (9.79)

n/a

Median age (IQR; months)

17.5 (7.2–35.4)

14.3 (5.2–31.8)

0.0001

Mean WAZ (95% CI)

−1.69 (−1.71, −1.67)

−1.59 (−1.66, −1.52)

0.0075

Mean HAZ (95% CI)

−1.33 (−1.36, −1.30)

−1.30 (−1.39, −1.22)

0.613

Mean parasite density (95% CI; parasites/mcl)a

28,597 (27,015–30,270)

10,002 (7686–13,015)

<0.0001

Mean hemoglobin (95% CI g/L)

91.4 (90.9–91.9)

98.0 (96.6–99.3)

<0.0001

Mean MCV (95% CI)

74.1 (73.9–74.3)

72.5 (71.8–73.2)

<0.0001

Median WBC (IQR; ×109/mcl)

12.0 (8.7–16.7)

12.9 (9.1–17.7)

<0.0001

Median platelets (IQR; ×106/L)

273 (134–442)

373 (227–528)

<0.0001

  1. The data summarized reflect the clinical and laboratory features of hospital-admitted case-patients only, stratified by HbS genotype. P values estimated by use of Student’s t test, χ2, or Mann–Whitney tests as appropriate in comparison to HbAA children
  2. WAZ weight-for-age Z-score, HAZ height-for-age Z-score
  3. aGeometric mean densities among children with positive slides (7222 (43.8%) of HbAA and 384 (21.4%) of HbAS children)
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