Fig. 5

Scope of C3-functionalized indoles. Reaction conditions: 5 (1 mmol), 2 (2.5 mmol), CuSO₄ (2 mol %), ^tBuOK (2.5 mmol), dioxane (0.75 mL). ^a2 (5 mmol), ^tBuOK (4 mmol), octane (0.75 mL) instead of dioxane. ^b2 (1.5 mL) was used as solvent. ^cCuSO₄ (10 mol %) was used. ^dDioxane (1.5 mL). ^e2 (15 mL) was used as solvent. ^fCuSO₄ (20 mol %) was used. ^gDioxane (20 mL). ^htBuOK (4 mmol). ^itBuOK (4 mmol), no extra solvent. Brsm yield refers to the yield based on recovered starting material