Fig. 2 | Nature Communications

Fig. 2

From: Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

Fig. 2

Coordinated upregulation of Claspin, Timeless, and CHK1 protein levels in cancer cell lines. a Western blot analysis of the levels of Claspin, Timeless, CHK1, and ATR in human cancer cell lines (U2OS, HeLa, and HCT116) and in immortalized primary fibroblasts (IMR90). b Claspin, Timeless, CHK1, RAD17, and ATR in colorectal cancer HCT116 cells, immortalized primary fibroblasts (BJ) and immortalized epithelial cells (RPE-1 and MCF10A). c Correlation analysis of the abundance of DDR proteins in 50 colorectal cancer cell lines

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