Fig. 1

Overall αβTCR sequence overlap comparisons among various MHCr and MHCi repertoires. a, b Percentage of TCRβ (a) and TCRα (b) sequence overlaps observed within each strain of B6, B10.BR, BALB/c, Quadko (Q), or QuadkoBcl-2tg (QB) animals. c, d Percentage of TCRβ (c) and TCRα (d) sequence overlaps observed between different strains of animals. The pair-wise sequence overlapping percentages are calculated using top 100, 200, 500, 1000, 2000, 10,000, 40,000 highest frequency and all sequences of each strain, respectively. e TCRβ and TCRα common sequences overlapping among the top 3000 sequences from B6, B10.BR, BALB/c, Quadko (Q), or QuadkoBcl-2tg (QB). f, g The distribution of average length of CDR3β (f) and CDR3α (g) in MHCr and MHCi TCR repertoires with respect to their frequency intervals. Sequences from each strain were grouped by 5% intervals from the top 5% frequent sequences until the accumulation of all sequences (100%). The error bars indicate standard deviations from the means. The p-values all figures are calculated using unpaired student t-test with * = p ≤ 0.05, ** = p ≤ 0.01, *** ≤ 0.001, **** = p ≤ 0.0001. The results included in all panels are from at least two independent experiments with all data included