Fig. 3 | Nature Communications

Fig. 3

From: Molecular constraints on CDR3 for thymic selection of MHC-restricted TCRs from a random pre-selection repertoire

Fig. 3

Sequence diversity and CDR3 length distributions. a TCRβ species richness of various TCRβ repertoires based on Chaobc1 analysis. b The inverse simpson index (ISI) was calculated to estimate the clonal diversity of various TCRβ repertoires. c TCRβ sequence overlapping among the top 3000 common sequences to B6 DP1 from B6, B10.BR, BALB/c, Quadko (Q), or QuadkoBcl-2tg (QB). d, e Heatmap showing CDR3 length distributions of TCRβ (d) and TCRα (e) for various MHCr, MHCi and pre-selection repertoires. The mice are identified with a number associated with their strain name (Table S1-S2). For strains with more than three sequencing attempts, only three repertoires are shown here

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