Fig. 6 | Nature Communications

Fig. 6

From: Discovery of key whole-brain transitions and dynamics during human wakefulness and non-REM sleep

Fig. 6

Mean activation distributions of sleep-related HMM states. a HMM states associated with N1 sleep showed opposite signs in mean activation in subcortical areas and primary sensory areas of the cortex. b Three HMM states related to N2 sleep. HMM states 3 and 6 in particular showed peak increases and decreases, respectively, in areas previously identified as fMRI-correlates of sleep spindles. c HMM state 16 is dominating slow wave sleep (N3). Interestingly, there are marked decreases in mean activation in frontal areas and insula, and very localised increases in the supplementary motor area and paracentral lobule. All maps were thresholded above the 50% strongest positive and negative changes, respectively

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