Fig. 8
From: Assessing the causal association of glycine with risk of cardio-metabolic diseases
Forest plot of the odds ratios ± 95% confidence intervals for type 2 diabetes per standard deviation genetically predicted higher levels of glycine using four different genetic scores for glycine. Genetic estimates are based on 74,124 T2D cases and 824,006 controls for sex-combined analyses. Sex-specific genetic analyses include 12,013 female and 16,914 male T2D cases and 202,124 female and 164,944 male controls. For the sex-specific analyses, the standard deviations of the sex-specific glycine distributions were used, which were 0.321 and 0.195 (arbitrary units) for women and men in the EPIC-Norfolk study, respectively. Results based on the weighted median MR method are shown
