Fig. 2 | Nature Communications

Fig. 2

From: Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis

Fig. 2

Fibril protein β-sheet structure. a Ribbon representation of a stack of five fibril proteins rainbow colored from N-terminus to C-terminus. b Close-up of the parallel cross-β sheet β1. c Position of the β-strands (arrows) in the fibril protein and in the natively folded LC as defined in PDB entry 1BJM60. Residue numbers refer to the native LC without signal sequence. The color of the β-strands in the fibril corresponds to panel a. Dotted gray line refers to the part of the protein that is disordered in the fibril. d Schematic representation of the fibril protein packing

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