Fig. 6
From: Inner lumen proteins stabilize doublet microtubules in cilia and flagella

MIP3a is important for B-tubule anchoring to the A-tubule at inner junctions. a Differential interference contrast (DIC) images of wild type, fap20, fap20fap45, fap20fap52, and fap20fap45fap52 cells. Scale bar = 10 μm. b Box and whisker plots of flagellar length in wild type, fap20, fap20fap45, and fap20fap52. fap20fap52 and fap20fap45fap52 flagella were significantly shorter than in wild type, fap20, and fap20fap45. The whiskers represent 95% confidence intervals. The box represents the interquartile range and the center line shows the median. c Cross-sectional EM images of fap20, fap20fap45, fap20fap52, and fap20fap45fap52 axonemes. Arrowheads indicate disconnections between the A-tubule and B-tubule. Scale bar = 100 nm. d Cross-sectional images of fap20, fap20fap45, fap20fap52, and fap20fap45fap52 DMTs. Scale bar = 50 nm