Fig. 5
From: UFL1 promotes histone H4 ufmylation and ATM activation
Ufmylation of histone H4 enhances trimethylation of H3K9 at DSB. a, b Analysis of H3K9 trimethylation and Suv39H1 recruitment by Chromatin IP (ChIP) at DSB sites from MDA-MB-231 ROS8 cells with indicated treatments. The y-axis represents relative enrichment of target protein binding DNA compared to input. Target sequence of UFL1 shRNA (not inducible shRNA) in a is the same as inducible sh2. The data presented are mean ± s.e.m. for n = 3 independent experiments. **p < 0.01. Statistical significance was calculated using one-way ANOVA. Source data are provided as a Source Data file
