Fig. 3
From: Clonal architectures predict clinical outcome in clear cell renal cell carcinoma
The temporal order of mutation acquisitions during ccRCC evolution. a The distributions of cancer cell fraction (CCF) values for the frequent somatic events. The median CCF value is shown for each gene or SCNA (red dots represent the medians and bars represent 95% confident intervals). b The temporal maps of mutation acquisitions in ccRCC. Temporally direct edges are drawn when two drivers are found in the same sample, one in clonal and the other in subclonal. Only driver pairs with at least five connecting edges were tested for statistical significance
