Fig. 5

Building block-based synthesis of all possible Csp3 stereoisomers of xylarinic acid B. a Conditions for deprotection and coupling. b Air-stable BIDA boronate building blocks prepared by resolution. c Xylarinic acid B and all possible Csp3 steroisomers accessed by stereospecific cross-coupling of stereodefined building blocks. % ds, b/l, and yield refer to the cross-coupling step