Fig. 5
From: A post-translational modification of human Norovirus capsid protein attenuates glycan binding
Binding of blood group B trisaccharide to GII.4 Saga P-dimers. a 1H,15N, TROSY HSQC spectra of native (red, left) and deamidated (blue, right) Saga P-dimers in their free forms and in the presence of 20 mM B trisaccharide (orange). Perturbations induced by ligand binding are indicated by arrows for selected amino acids. b Mapping of chemical shift perturbations (CSPs) for both forms onto the crystal structure of P-dimers complexed with B trisaccharide (pdb: 4X06). c Complete chemical shift mapping of the respective P-dimer species with experimentally determined 7.9 Hz significance thresholds and additional 2σ threshold to indicate largest CSPs in native P-dimers. Source data are provided as a Source Data file
