Fig. 7
From: A post-translational modification of human Norovirus capsid protein attenuates glycan binding
Binding of methyl α-l-fucopyranoside to deamidated GII.4 Saga P-dimers. Wall-eyed stereo representation of the crystal structure showing a non-canonical binding mode of methyl α-l-fucopyranoside in the modified binding pocket. The 2FO − FC map is shown (σ level = 1.0). a For one chain the isopeptide bond (isoD373) and the ligand are clearly visible. b For the other chain the loop bordering the binding pocket is unstructured N-terminally of D374, and a canonical binding mode is observed. A corresponding ligand interaction diagram and data collection and refinement statistics are found in Supplementary Note 5 (Supplementary Fig. 23 and Supplementary Table 11)
