Fig. 2 | Nature Communications

Fig. 2

From: Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma

Fig. 2

Heterogeneity of amplification/deletion drivers in ESCC. a Heat map shows somatic CNAs with different clonal status. The right bar represents the proportion of identified as trunk/branch in ESCC; the bottom panel shows genome doubling status of each patient; the top panel shows the percentages of trunk or branch CNAs. b Clonal evolution in case ESCC033. The left panel shows phylogenetic tree based on somatic SNVs. Asterisk segments represent SNVs from intermixed clone; the right panel shows the CCF of segment mutation 2*. Black: trunk; blue: shared branches; red: private branches

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