Table 1 Summary of data

From: Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density

 

Mean (SD)

Men’s mean (SD)

Women’s mean (SD)

Sex effect

Sex P-value

Glaucoma effect [SD]

Glaucoma P-value

 CD

2652 (296)

2639 (296)

2663 (294)

23.83

1.8 × 10−3

−0.35

2.1 × 10−6

 CV

30.0 (5.9)

29.6 (6.7)

30.3 (5.1)

0.71

2.6 × 10−6

0.13

0.069

 CCT

563 (40)

565 (40)

562 (39.5)

−3.82

1.9 × 10−4

−0.25

4.7 × 10−4

 HEX

49.3 (6.5)

50.6 (6.6)

48.3 (6.3)

−2.29

8.4 × 10−43

−0.16

0.030

 CH

10.4 (1.2)

10.2 (1.2)

10.5 (1.1)

0.28

5.7 × 10−22

−0.37

3.8 × 10−7

 IOPg

14.7 (3.4)

14.6 (3.5)

14.7 (3.4)

0.13

0.15

0.18

0.014

 IOPcc

15.3 (3.1)

15.4 (3.2)

15.2 (3.0)

−0.19

0.015

0.29

7.3 × 10−5

 CRF

13.1 (1.5)

13.0 (1.5)

13.3 (1.5)

0.29

5.7 × 10−14

−0.07

0.34

  1. The mean and standard deviation (SD) is shown for each corneal trait obtained from the specular microscopy equipment and the ocular response analyzer, overall and separately for each sex. The effect of sex and glaucoma status on each trait and the corresponding P-values (F test) are shown. The sample size was 6125 in total, 2733 men and 3392 women
  2. CD cell density, CV coefficient of cell size variation, CCT central corneal thickness, HEX percentage of hexagonal cells, CH corneal hysteresis, IOPg Goldmann correlated intraocular pressure, IOPcc corneal compensated intraocular pressure, CRF corneal resistance factor