Table 1 Summary of crystallographic structure determination statistics

 Space group

I121

I4

P12₁1

P4₃2₁2

P4₃2₁2

  a, b, c (Å)

90.8, 46.0, 134.2

74.3, 74.3, 52.0

46.8, 92.8, 47.0

54.5, 54.5, 83.6

60.3, 60.3, 85.2

  α, β, γ (°)

90, 105.6, 90

90.0, 90.0, 90.0

90.0, 91.3, 90.0

90.0, 90,0, 90.0

90.0, 90,0, 90.0

 Resolution (Å)

43.76–2.26 (2.34–2.27)

42.59–2.009 (2.06–2.01)

47.03–2.52 (2.62– 2.52)

45.65–2.35 (2.43–2.35)

49.22–2.83 (2.98–2.83)

 R_merge

0.151 (0.894)

0.122 (0.181)

0.062 (0.684)

0.076 (1.074)

0.094 (0.728)

 R_pim

0.063 (0.540)

0.035 (0.051)

0.039 (0.428)

0.015 (0.216)

0.028 (0.210)

 < I > / σI

10.7 (2.5)

13.9 (9.1)

8.8 (1.3)

20.9 (3.1)

14.4 (2.6)

 Total observations

187434 (15896)

126993 (9306)

46543 (5123)

147768 (12430)

50092 (7141)

 Unique observations

25107 (2222)

9533 (682)

13562 (1488)

5645 (505)

4100 (565)

 Completeness (%)

99.7 (97)

99.9 (99.3)

99.0 (96.7)

99.4 (94.3)

99.4 (96.2)

 Multiplicity

7.5 (7.2)

13.3 (13.6)

3.4 (3.4)

26.2 (24.6)

12.2 (12.6)

 Half-set correlation (CC(1/2))

0.996 (0.726)

0.997 (0.990)

0.998 (0.706)

1.000 (0.982)

0.999 (0.960)

 R_work/R_free

0.186/0.238

0.187/0.213

0.175/0.247

0.244/0.299

0.280/0.314

  Protein

2676

961

6584

834

860

  Solvent

57

22

22

9

2

 Average B-factor (Ų)

26.3

27.1

80.7

79.0

103.7

  Bond lengths (Å)

0.017

0.008

0.010

0.006

0.002

  Bond angles (°)

1.312

0.980

1.520

1.036

0.536

  Favored

97.0

97.0

97.0

98.0

90.0

  Allowed

2.7

3.0

2.2

1.0

9

  Outliers (%)

0.3

0

0.8

1.0

1.0

  Clash score

8

5

8

1

1