Fig. 2
From: Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects
Rate of side effect (SE) manifestation across drug-SE combinations classified by genetic support. OR, odds ratio; P, P-value from Fisher’s exact test (two-tailed). The left panel shows analyses based on all 38,199 drug-SE combinations; the right panel shows analyses based on 33,489 “off-indication” drug-SE combinations. Error bars represent the 95% confidence interval of the reported proportions. Source data and confidence intervals for the OR values are shown in Supplementary Table 1. Similar analyses for Mendelian and GWAS genetics separately are shown in Supplementary Figure 4
