Fig. 3 | Nature Communications

Fig. 3

From: Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

Fig. 3

Affinity of 1 for PreQ1-RS aptamers. a Fluorescence intensity assay of 5′-Cy5-labeled BsPreQ1-RS or 5′-AlexaFluor 647-labeled TtPreQ1-RS RNA in the presence of increasing concentration of 1. b Inherent fluorescence titration of 1 with increasing concentration of unlabeled BsPreQ1-RS or TtPreQ1-RS RNA. Error bars indicate the standard deviation determined from three independent measurements. Source data are provided as a Source Data file

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