Fig. 3
From: Lower synaptic density is associated with depression severity and network alterations
Functional connectivity and combined connectivity/PET results. a Significantly lower dlPFC ICD connectivity in clinical (n = 26) vs. HC group (n = 13). Error bars represent standard deviation. dlPFC region displayed on right, subsequently used as seed. b Negative correlation between dlPFC-PCC connectivity and dlPFC SV2A density in the clinical group. Significant voxels represent those voxels whose connectivity with the dlPFC negatively correlates with [11C]UCB-J VT in the dlPFC. c Positive correlation between dlPFC-PCC connectivity and severity of depressive symptoms. Correlations were computed using Pearson’s r. dlPFC: dorsolateral prefrontal cortex, PCC: posterior cingulate cortex, ICD: intrinsic connectivity distribution
