Fig. 5

Model incorporating FN1 recaptures EMT dynamics. a Graph illustrating the EMT-regulatory circuit incorporating FN1. Dotted lines represent ceRNA interactions. b Bifurcation analysis using the original EMT model of Zhang et al.²⁶. c Bifurcation analysis using the original EMT model of Zhang et al. with an increased miR-200c half-life. Specifically, the parameters controlling the recycling rates of miR-200c in the miR-200c-ZEB1 complexes increased from 0.5 to 0.9. d Bifurcation analysis using the EMT model incorporating FN1. e Bifurcation analysis simulating FN1 knockdown. Specifically, the FN1 degradation rate constant in the EMT model incorporating FN1 increased to 1