Table 1 Demographics and descriptive statistics for the GWAS sample, N = 7045

From: A PRPH splice-donor variant associates with reduced sural nerve amplitude and risk of peripheral neuropathy

 

Males

Females

P*

Total

N (%)

3140 (44.6)

3905 (55.4)

-

7045 (100)

Age, M (SD)

54.4 (15.1)

54.9 (14.4)

0.51

55.7 (14.8)

SNAP, M (SD)

11.3 (7.2)

10.3 (6.2)

6.2 × 10−11

10.7 (6.6)

SNCV, M (SD)

50.0 (5.7)

54.0 (6.0)

1.8 × 10−166

52.2 (6.2)

Chronic pain, N (%)

181 (5.8)

376 (9.6)

1.7 × 10−9

557 (7.9)

  1. N = 6879 with SNAP (sural nerve action potential, amplitude, μV) and N = 6979 with SNCV (sural nerve conduction velocity, m s−1), chronic pain (≥3 months, by self-report). M mean, SD standard deviation *Significance tests: Chi-square test for chronic pain and two-sided t-test for age, SNAP, and SNCV
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