Fig. 3 | Nature Communications

Fig. 3

From: Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9

Fig. 3

Structural comparison of the Cas9 orthologs. The structures of Corynebacterium diphtheriae Cas9 (CdCas9), Campylobacter jejuni Cas9 (CjCas9) (PDB: 5X2G), Staphylococcus aureus Cas9 (SaCas9) (PDB: 5CZZ), Streptococcus pyogenes Cas9 (SpCas9) (PDB: 4UN3), and Francisella novicida Cas9 (FnCas9) (PDB: 5B2O) bound to their cognate single-guide RNA (sgRNAs) and target DNAs, and the structure of Actinomyces naeslundii Cas9 (AnCas9) in the apo form (PDB: 4OGE). The bridge helix and the linker regions are colored green and light green, respectively

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