Fig. 5
PI3K pathway activation versus T cell infiltration. a PTEN loss and PIK3CA amplification were enriched in immune LOW and MIX group SQCC (immune group red, yellow, and blue for HIGH, MIX, and LOW). b Comparison of PTEN and PIK3CA alteration with T cell signature. c Comparison of PTEN and PIK3CA alteration with CD8 IHC H-score. d PIK3CA expression versus T cell signature, amplification/high expression (red) was associated with low T cell signature. The top and bottom of the boxes are the lower and upper quartiles. The middle line in the box is median, and the whiskers are lowest and highest point within 1.5 times the interquartile range of the lower and upper quartile. e PTEN expression versus T cell signature, loss/low expression (blue) was associated with low T cell expression. Source data are provided as a Source Data file
