Fig. 3 | Nature Communications

Fig. 3

From: Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery

Fig. 3

Shigella flexneri invades epithelia cells in a T3SS-dependent manner. a, b Representative images of colonic sections immuno-stained for E-cadherin and S. flexneri. a Merge: E-cadherin, green; S. flexneri, red. b S. flexneri only. Arrows indicate intracellular S. flexneri. Scale bars, 50 μm. c Zoom-in on the boxed area in a. d Graph showing counts of colony-forming units in the distal colon of animals infected with S. flexneri (wild-type (WT)) or the T3SS mutant (ΔmxiG). Statistical analysis, unpaired t test. ΔmxiG vs. WT, ***P < 0.0005. Source data are provided as a Source Data file

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