Fig. 4
From: Regulation of locomotor speed and selection of active sets of neurons by V1 neurons
Voltage-clamp recordings from slow-type motoneurons (MNs) in control and En1-DTA fish. a Example of simultaneous recordings between slow-type MNs (voltage-clamp) and ventral root (VR) in control fish. The cell was held at −75 mV to reveal excitatory currents. b Example of simultaneous recordings between slow-type MNs and VR in control fish. The cell was held at +10 mV to reveal inhibitory currents. The right two panels show the enlargements of the regions shaded in blue. “In” represents the in-phase period (from −0.15 to +0.15 in the cycle, pink). “Anti” represents the anti-phase period (from 0.35 to 0.65, gray). c Example of simultaneous recordings between slow-type MNs and VR in En1-DTA fish. The cell was held at −75 mV to reveal excitatory currents. d Example of simultaneous recordings between slow-type MNs and VR in En1-DTA fish. The cell was held at +10 mV to reveal inhibitory currents. e Phase analysis of excitatory and inhibitory currents during fast/strong swim. Normalized currents (±s.e.m.) are shown. Top panel, control fish; bottom panel, En1-DTA. f, g Peak inhibitory (f) and excitatory (g) currents during fast/strong swim in control (left, n = 10) and En1-DTA (right, n = 11) fish. “In” represents the in-phase period. “Anti” represents the anti-phase period. Each circle represents each cell. **P < 0.01; *P < 0.05 (comparison between control and En1-DTA, Mann–Whitney U test, P = 0.0080 [f], P = 0.013 [g]; comparison between in-phase and anti-phase, Wilcoxon signed-rank test, P = 0.0020 [f, control], P = 0.0029 [f, En1-DTA], P = 0.0020 [g, control], P = 0.00098 [g, En1-DTA])
