Fig. 1 | Nature Communications

Fig. 1

From: Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis

Fig. 1

B. fragilis PSA protects against HSE. a Experimental regimen: In all experiments, PSA (six doses, 50 μg/mouse) or PBS was given orally before HSV infection on day 0 and thereafter daily ip injections of ACV from day 4 pi for 7 days. Survival of wildtype (WT) or Rag mice pre-treated with b B. fragilis, PSA or c PBS, (n = 8–17 mice/group). ****p < 0.001, WT + B. fragilis/PSA vs. Rag + PSA; ns: not significant, WT + PBS vs. Rag + PBS as determined by log rank (Mantel–Cox) test

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