Table 1 Binding specificity for 20 commercial mAbs using VirD-GPCR arrays
From: Development and application of a high-content virion display human GPCR array
mAbs | Provider | Assays on the datasheet | GPCR-VirD array results | Z-score |
|---|---|---|---|---|
α-CCR7 | R&D System | Neutralization; Flow; IFC | Specific | 16.5 |
α-CXCR1 | R&D System | Neutralization; Flow; IHC | Specific | 9.2 |
α-CXCR2 | R&D System | Neutralization; Flow; IHC | Specific | 15.6 |
α-CXCR5 | R&D System | Neutralization; Flow; IFC; IHC | Specific | 11.4 |
α-GPRC5C | R&D System | Flow | Specific | 16.1 |
α-ACKR1 | R&D System | Flow; IFC | Specific | 18.1 |
α-LTB4R | R&D System | Flow | Specific | 13.4 |
α-SSTR2 | R&D System | Flow; IFC; IHC | Specific | 11.8 |
α-MRGPRF | R&D System | Flow; WB | Specific | 10.8 |
α-ACKR3 | R&D System | Flow; IHC | Specifica | 14.0 |
α-DRD1 | R&D System | Flow; IHC | Nonspecific | 2.2 |
α-CCR1 | R&D System | Flow | Nonspecific | 1.5 |
α-CCR2 | R&D System | Flow, IHC | Nonspecific | -0.5 |
α-CCR4 | R&D System | Flow | Nonspecific | 1.4 |
α-CCR9 | R&D System | Flow; IFC; IHC | Nonspecific | 0.8 |
α-CXCR6 | R&D System | Flow | Nonspecific | −0.7 |
α-S1PR1 | R&D System | Flow | Nonspecific | 1.2 |
α-APLNR | R&D System | Flow; IHC | Nonspecific | 2.4 |
α-P2RY11 | R&D System | Flow | Nonspecific | 2.7 |
α-P2RY13 | ProMab | Flow, ELISA, WB | Nonspecific | 1.0 |
