Table 1 Glossary of terms
From: Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
Term | Meaning |
|---|---|
CSF | Cerebrospinal fluid |
IPD | Invasive pneumococcal disease |
GWAS | Genome-wide association study |
hGWAS | Host genome-wide association study |
pGWAS | Pathogen genome-wide association study |
h 2 | Heritability (variation in phenotype explained by genetic variation) |
OR | Odds ratio |
LD | Linkage disequilibrium |
MAF | Minor allele frequency (of the least common allele observed in the population) |
AF | Allele frequency (presence of gene or versus reference allele) |
LoF | Loss of function (frameshift or nonsense mutation in protein) |
SFS | Site frequency spectrum (histogram of minor allele frequencies) |
LMM | Linear mixed model (association model used in genome-wide association study) |
eQTL | Expression quantitative trait loci (genetic association with transcript variation) |
LD | Linkage disequilibrium |
