Fig. 4 | Nature Communications

Fig. 4

From: CUT&Tag for efficient epigenomic profiling of small samples and single cells

Fig. 4

CUT&Tag profiling of the NPAT chromatin factor and chromatin accessibility. a Ideograms of chromosome 1 and chromosome 6 with the clusters of replication-dependent histone genes (6 genes at 1q21.2 and 55 genes at 6p22.2) indicated. An NPAT CUT&Tag profiling track is displayed over each chromosome. The major NPAT peaks fall at the histone genes. b Distribution of read counts in CUT&Tag profiling. Called accessible sites from ATAC-seq data were segregated into those at histone genes and other ATAC sites. Read counts from NPAT CUT&Tag were plotted for each category. c Boxplots of NPAT CUT&Tag signal at the promoters of replication-dependent histone genes (His), at other accessible sites called from ATAC-seq data, and at a random selection of genomic background sites (bkgd). Source data are available in the Source Data file

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