Fig. 4
From: Flexible and scalable diagnostic filtering of genomic variants using G2P with Ensembl VEP
Comparison of VEP-G2P to existing tools. a Comparison for 100 random DDD samples with dominant de novo sample (left panel) and 100 random DDD recessive samples (right panel). b Comparison for 100 unaffected Generation Scotland (GS) samples. Each dot represents the rank of the causative gene in the output of the tools, where rank of 1 indicates the causative gene is at the top of the list reported by the tool; boxplots show the median (centre line), the first and third quartiles (box bounds), whiskers represent 1.5∗ interquartile range from the first/third quartiles. F1 = 2∗((precision∗recall)/(precision + recall))
