Fig. 1 | Nature Communications

Fig. 1

From: Lnc-TALC promotes O6-methylguanine-DNA methyltransferase expression via regulating the c-Met pathway by competitively binding with miR-20b-3p

Fig. 1

LncRNA microarray detection of TMZ-resistant and parental GBM cells. a Schematic process to acquire TMZ-resistant GBM cells and to screen the lncRNA lnc-TALC. b The circos plot presents the genome-wide view of the top 30 up- or downregulated lncRNAs and the associations with mRNAs of TMZ-resistant GBM cells. c The heatmap shows the top 30 up- and downregulated lncRNAs in TMZ-resistant GBM cells. d The top 30 upregulated lncRNAs associated with functional gene sets of TMZ-resistant GBM cells are shown in the heatmap. e The top 10 upregulated lncRNAs between LN229 and 229R cells are listed in the volcano plot

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