Fig. 2

Promoter vs gene body mutations and their effect on MIC (y axis in mg per L) for four drugs (n = 1452). Wilcoxon rank sum test comparing each pair was significant at p < 0.01. For reference critical resistance testing concentration is 0.2 mg per L for INH, 5 mg per L for ETA, 100 mg per L for PZA, 5 mg per mL for EMB and indicated by the horizontal dotted line. Figure 2 can be regenerated using code in Supplementary Data 8 that will refer to data items provided in the Source Data file (compressed source data folder)