Fig. 5

Reducing ubH2A couples with an effect to promote adult fitness. Analysis of adult phenotypes reveals that Sce^c244/ + single mutants and Sce^c244/ + ; Su(z)2^c433/ + double mutants have better climbing (a) and enhanced resistance to oxidation (b) than age-matched WT. (for climbing assay: mean ± s.e.m. of 10 biological repeats with 10 male flies for each repeats; student t test; for oxidation tests: 25 °C, n > 100 male flies per genotype for curve, log-rank test). Genotypes (fly total number (death / censored)): WT: 5905 (196 (196 / 0)). Sce^c244/ + (245 (245 / 0)). Sce^c244/ + ; Su(z)2^c433/ + (202 (201 / 1))