Fig. 5
From: Structural basis for substrate gripping and translocation by the ClpB AAA+ disaggregase
3D focus classification reveals substrate interaction with NTDs. a Views of the NTD-focused refinement map after particle re-centering, colored by protomer, showing the P1–P3–P5 trimeric NTD ring. b Model of the P1–P3–P5 NTD trimer, and substrate polypeptide, modeled as poly-Ala (cyan), that extends from the P5 NBD1 pore loop (Y251). c Model of P5 and P3 NBDs interacting with substrate. Substrate-interacting helices A1 and A6 (magenta), previously characterized36, are shown
