Fig. 4 | Nature Communications

Fig. 4

From: Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique

Fig. 4

The STRING networks of proteins with regulated SNO sites after GSNO treatment of HeLa extracts. N = 3 biological replicates. a Proteins with significantly downregulated SNO sites, b the 500 proteins with the strongest upregulated SNO sites. Both networks indicate the role of SNO in splicing, translation, ubiquitin mediated proteolysis, DNA replication, cellular response to stress, vesicle-mediated transport, GTPase-mediated signaling and aminoacyl-tRNA biosynthesis pathways. Source data are provided as a Source Data file

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