Fig. 3
From: Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase
The BG loop of SOCS2. a Secondary structure elements in SOCS2 are shown above the sequence alignment, numbering of residue is for SOCS2. SOCS proteins with crystal structures available were aligned using T-Coffee expresso mode for sequence alignment with structural information87. b Locations of the EF loop (orange) and the BG loop (green) on SOCS2 (white) crystal structure with bound GHR peptides A and B (cyan and yellow, respectively). c The Fo-Fc omit map of the previously disordered region of the BG loop (green mesh) contoured at 1.5 σ level
