Fig. 6
From: Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly
Effect of combined ciclopirox and TDF and ETV on replication of HepG2.2.15 cells. HepG2.2.15 cells were treated with 1 μM TDF or ETV and various concentrations (0.1–10 μM) of ciclopirox. a–d Secreted HBV DNA (a, c, respectively) and intracellular HBV DNA (b, d, respectively) were measured by quantitative PCR. Combination indices (CI) were analyzed by the Chou-Talalay method. The data in (a–d) are representative of three independent experiments and are expressed as mean ± SD. The error bars represent the ± SD. *p < 0.05; **p < 0.01, by unpaired two-tailed Student’s t-tests. Source data are provided as a Source Data file
