Fig. 4
From: Model-based understanding of single-cell CRISPR screening
Evaluating the impact of the data preprocessing strategies adopted in MUSIC. a The proportion of filtered cells by quality control for all datasets. The red dash line represents the mean of the data. b The proportion of filtered cells by filtering low efficiency sgRNA for all datasets. The red dash line represents the mean of the data. c zero_rate plot of all knockouts/knockdowns in all datasets. The red dash line represents the mean value of all the knockouts/knockdowns zero_rates. d Comparisons of overall perturbation effect ranking with or without imputation/filtering for all the available datasets
