Fig. 2
Characteristics of respiratory virome among children with single or multiple ARTIs. Detection and co-detection rates were compared by Fisher’s exact test for common respiratory viruses (a), pathogenic respiratory viruses (excluding the persistent DNA viruses: herpesviruses, polyomaviruses, papillomaviruses, species C adenoviruses and adeno-associated virus) (d), and anelloviruses (g). The viral alpha diversity (Shannon Diversity Index) were analyzed using nonparametric Kruskal-Wallis Test correcting for multiple comparisons with Dunn’s procedure for common respiratory viruses (b), pathogenic respiratory viruses (e) and anelloviruses (h). The viral richness (Chao Richness score) were analyzed using nonparametric Kruskal-Wallis Test corrected for multiple comparisons with Dunn’s procedure for common respiratory viruses (c), pathogenic respiratory viruses (f), and anelloviruses (i). The number of samples in each group were 48 (single ARTI), 164 (multiple ARTIs), 61 (1st), 61 (2nd), 32 (3rd), 10 (4th) (as only one sample was in the 5th episode, we combined the 5th episode into the 4th episode group). The results were presented as box and whiskers plots. The central line shows the median, and whiskers above and below the box show the minimum and maximum within 1.5 interquartile range (IQR) of the lower quartile and the upper quartile
